Acquisition of heme iron by Neisseria meningitidis does not involve meningococcal transferrin-binding proteins.
نویسندگان
چکیده
Similarities in size between hemin-binding protein 1 (HmBP1) and transferrin-binding protein 1 (TBP1) of Neisseria meningitidis suggest that these proteins are functionally homologous. However, a meningococcal mutant lacking the transferrin-binding proteins retained the capacity to acquire iron from heme and hemoglobin. In immunoblots, hyperimmune polyclonal antiserum against TBP1 did not react with HmBP1.
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ورودعنوان ژورنال:
- Infection and immunity
دوره 62 2 شماره
صفحات -
تاریخ انتشار 1994